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The Hidden Biology of
Irritable Bowel Syndrome,
by
Zachary Spiritos, MD, MPH neurogastroenterologist
of

EverBetterMedicine.Health

Clinician's Roundtable Recording & more ​
March 27, 2026

About

Dr. Spiritos shares about IBS being a disorder of altered signaling, about neuro-immune-autonomic dysfunction driving visceral hypersensitivity and he encourages a shift in clinical model from symptom management to mechanism based care. This talk was announced as "When the Gut-Brain Axis Goes Wrong: Mast Cells, Histamine, and Practical Clinical Management." Featured are IBS, hypermobility, ME/CFS, Long Covid, MCAS, research, treatment, and clinical approach.

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Time codes in chat are the time of day, not the time in the recording. 13:00 is roughly when webinar started.

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